Publications

2026

Gregory Valentine: ECI biocommentary

Valentine GC. Pediatr Res. 2026 Feb;99(3):832-833. doi: 10.1038/s41390-026-04777-z. Epub 2026 Jan 15. PMID: 41540199.

Body composition using point-of-care ultrasound in infants admitted to the neonatal intensive care unit

Yeager S, Hendrixson T, Cunha G, Valentine GC, Strobel KM. The Journal of Perinatology. doi: 10.1038/s41372-026-02730-w.

Periodontitis and adverse pregnancy outcomes: mechanistic evidence

Valentine GC, Bobetsis YA, Shayo BC, Milgrom P, Madianos PN. Journal of Periodontal Research. doi: 10.1111/jre.70134

Disparities in neurodevelopmental care for at-risk newborns

Neches SK, Woods M, Perez KM, Germann K, Mietzsch U, Feltner J, Natarajan N, Trevino C, Penders R, Emhoff S, Stein B, Juul SE, Collett BR, Valentine GC. Res Sq [Preprint]. 2026 May 20:rs.3.rs-9475637. doi: 10.21203/rs.3.rs-9475637/v1. Update in: J Perinatol. 2026 Aug 10. doi: 10.1038/s41372-026-02870-z. PMID: 42239774; PMCID: PMC13228826.

A dilemma of parental inclusion? Parent perspectives of NICU feeding practices and neonatal nutritional research

Perez KM, Jochim A, Patel AL, Valentine GC. Semin Perinatol. 2026 Jun 24:152275. doi: 10.1016/j.semperi.2026.152275. Epub ahead of print. PMID: 42342486.

Initial nutrition in preterm infants: Evidence, uncertainty, and research priorities

Holzapfel LF, Thoene MK, Robinson DT, Valentine GC. Semin Perinatol. 2026 Jun 20:152274. doi: 10.1016/j.semperi.2026.152274. Epub ahead of print. PMID: 42323261.

2025

Design and Conduct of Global Health Research in Low- and Middle-Income Countries

Thayyil S, Bauserman M, Valentine GC, Patterson JK, Hoffman M, Aagaard K, Ramji S, Lokangaka A, Mhango J, Bhutta ZA, Shankaran S. J Pediatr. 2025 Jan;276:114268. doi: 10.1016/j.jpeds.2024.114268. Epub 2024 Aug 29. PMID: 39216623.

Oral health benefits and safety of xylitol and potential cardiovascular risk: questioning the validity of the model of Witkowski et al.

Valentine GC, Söderling E, Milgrom P. Eur Heart J. 2025 Mar 11:ehaf058. doi: 10.1093/eurheartj/ehaf058. Epub ahead of print. PMID: 40067657.

The Power of Professional Clinical Ethicists in Low- and Middle-Income Countries: An Ethiopian Perspective

Abadi M, Workneh R, Kukora S, Perez K, Valentine GC, Barbut G, Kassa BB, Abayneh M, Rent S. Am J Bioeth. 2025 Mar;25(3):95-98. doi: 10.1080/15265161.2025.2457692. Epub 2025 Feb 24. PMID: 39992837; PMCID: PMC11856426.

Effect of early antibiotic exposure on necrotizing enterocolitis and growth in extremely preterm infants

Strobel KM, Wood TR, Valentine GC, Brandon OC, Hendrixson DT, Mayock DE, Perez KM, Puia-Dumitrescu M, Heagerty PJ, Juul SE. Pediatr Res. 2025 Feb 15. doi: 10.1038/s41390-025-03928-y. Epub ahead of print. PMID: 39955429.

Neurodevelopmental outcomes after red cell transfusion exposure in male versus female extremely preterm infants

German K, Wood TR, Gogcu S, Heagerty P, Mayock DE, Comstock BA, Puia-Dumitrescu M, Kolnik S, Mietzsch U, Law J, Perez K, Valentine GC, Bammler TK, Juul SE. Pediatr Res. 2025 Jun 2. doi: 10.1038/s41390-025-04149-z. Epub ahead of print. PMID: 40456918.

Measuring ENAP interventions for small and/or sick newborns in routine health information systems: indicators and considerations from a WHO expert consultation

WHO expert consultative group on small and/or sick newborn indicators for Every Newborn Action Plan. J Glob Health. 2025 May 9;15:04134. doi: 10.7189/jogh.15.04134. PMID: 40341314; PMCID: PMC12062841.

A retrospective cohort study of premature neonatal mortality rates and contributing factors in a tertiary referral NICU in Addis Ababa, Ethiopia from 2022 to 2023

Valentine GC, Perez KM, Brandon OC, Rent S, Barbut G, Abadi M, Metaferia G, Workneh R, Abayneh M. Clin Epidemiol Glob Health. 2025 Jul-Aug;34:102118. doi: 10.1016/j.cegh.2025.102118. Epub 2025 Jul 7. PMID: 40746990; PMCID: PMC12311812.

Childhood differences in healthcare utilization between extremely preterm infants & the general population

Patel K, Wood TR, Horner D, Puia-Dumitrescu M, German K, Strobel KM, Perez K, Valentine GC, Law J, Comstock B, Mayock DE, Heagerty PJ, Juul SE, Kolnik SE. Children (Basel). 2025 Jul 25;12(8):979. doi: 10.3390/children12080979. PMID: 40868431; PMCID: PMC12385164.

Evaluation of first-week fluid intake and maximal weight loss percentage with in-hospital adverse outcomes among moderately and very preterm newborns in Ethiopia

Valentine GC, Rue T, Brandon OC, Perez KM, Wood TR, Rent S, Barbut G, Abadi M, Workneh R, Metaferia G, Abayneh M. Children (Basel). 2025 Jul 1;12(7):872. doi: 10.3390/children12070872. PMID: 40723065; PMCID: PMC1229342.

Post-hospital Discharge Nutrition for the Preterm Infant

Salas AA†, Valentine GC†, Buck C†, Gao M†, Martin CR, Hair AB. Current Treatment Options in Pediatrics. DOI: 10.1007/s40746-025-00342-8
†Co-first authors

The association between oral risk assessment and obstetric and newborn outcomes

Martinez-King C, Rose C, Perez KM, Brandon O, Sahota A, Nallaseth K, Yang TJ, Tibayan S, Kulkarni S, Hameed A, Gray KJ, Wood TR, Valentine GC. Pregnancy. 2025 Sep 29;1(6):e70114. doi: 10.1002/pmf2.70114. PMID: 42596995; PMCID: PMC13344603.

Force-Sensitive Resistors for Detecting Peripheral IV Failure

Wilson DM, Lorenzo L, Valentine GC. IEEE Sensors Letters. 9(10):1-4, Oct. 2025. doi: 10.1109/LSENS.2025.3605173.

Global prioritised indicators for measuring WHO’s quality-of-care standards for small and/or sick newborns in health facilities: development, global consultation, and expert consensus

Day LT, Vaz L, Semrau K, Moxon S, Niermeyer S, Khadka N, Chitashvili T, Valentine GC, Drake M, Ehret DE, Shefffel A, Sacks E, Greenspan L, Shaver T, Kak L, Hailegbriel T, Gupta G, Hill K, Jackson D. BMJ Open. 2025 Oct 20;15(10):e100338. doi: 10.1136/bmjopen-2025-100338. PMID: 41120171; PMCID: PMC12542562.

The prevention of developmental delay and xylitol (PDDaX) Trial: Study protocol of a nested cohort follow-up from the PPaX trial examining neurodevelopmental outcomes among offspring at 4-8 years of age in Malawi

Valentine GC, Collett B, Wallie S, Mhango J, Engmann C, Sullivan E, Seferovic M, Willoughby M, Shayo B, Walson JL, Milgrom P, Aagaard K, Juul SE. Trials. 2025 Nov 14;26(1):506. doi: 10.1186/s13063-025-09204-y. PMID: 41239527; PMCID: PMC12619221.

Early feeding and fluid volume associations with adverse in-hospital outcomes among premature newborns

Brandon OC†, Valentine GC†, Kolnik SE, Juul SE, Wood TR, Perez KM. Pediatric Research. 2025 Oct 27. doi: 10.1038/s41390-025-04494-z. Epub ahead of print. PMID: 41145633.
†Co-first authors

Time to regain birthweight and in-hospital outcomes among United States-born extremely preterm newborns

Valentine GC, Brandon OC, Perez KM, Strobel KM, Mayock D, Law J, Neches S, German K, Kolnik S, Heagerty P, Wood TR, Juul SE. Pediatric Research. 2025 Nov 10. doi: 10.1038/s41390-025-04563-3. PMID: 41214292.

Nutrition practices of neonatal intensive care units in the African Neonatal Network

Abayneh M, Yeshanew KH, Yidengitu SL, Tadesse RW, Ayomide A, Edwards EM, Ehret DEY, Henderson P, Kwima LN, Muzuva B, Nkuranga JB, Selam H, Siraha E, Stevenson AG, Tadesse M, Valentine GC. J Afric Neonatal. 2025;3:92-96. doi: 10.4314/jan.v3i3.5.

2024

Time to regain birthweight and association with neurodevelopmental outcomes among extremely preterm newborns

Valentine GC, Perez KM, Wood TR, Mayock DE, Law JB, Kolnik S, Strobel KM, Brandon OC, Comstock BA, Heagerty PJ, Juul SE. J Perinatol. 2024 Apr;44(4):554-560. doi: 10.1038/s41372-024-01869-8. Epub 2024 Jan 9. PMID: 38195922.

Contemporary definitions of infant growth failure and neurodevelopmental and behavioral outcomes in extremely premature infants at two years of age

Strobel KM, Wood TR, Valentine GC, German KR, Gogcu S, Hendrixson DT, Kolnik SE, Law JB, Mayock DE, Comstock BA, Heagerty PJ, Juul SE. J Perinatol. 2024 Jun;44(6):811-818. doi: 10.1038/s41372-023-01852-9. Epub 2024 Jan 9. PMID: 38195921; PMCID: PMC11161409.

Environmental Justice: A Missing Core Tenet of Global Health

Workneh R, Abadi M, Perez K, Rent S, Weiss EM, Kukora S, Brandon O, Barbut G, Rahiem S, Wallie S, Mhango J, Shayo BC, Saidi F, Metaferia G, Abayneh M, Valentine GC. Am J Bioeth. 2024 Mar;24(3):20-23. doi: 10.1080/15265161.2024.2303132. Epub 2024 Feb 23. PMID: 38394016; PMCID: PMC11146822.

Nutrition and the gut-brain axis in neonatal brain injury and development

Perez KM, Strobel KM, Hendrixson DT, Brandon O, Hair AB, Workneh R, Abayneh M, Nangia S, Hoban R, Kolnik S, Rent S, Salas A, Ojha S, Valentine GC. Semin Perinatol. 2024 Aug;48(5):151927. doi: 10.1016/j.semperi.2024.151927. Epub 2024 Jun 13. PMID: 38897828.

Non-nutritional use of human milk as a therapeutic agent in neonates: Brain, gut, and immunologic targets

Hoban R, Perez KM, Hendrixson DT, Valentine GC, Strobel KM. Early Hum Dev. 2024 Nov;198:106126. doi: 10.1016/j.earlhumdev.2024.106126. Epub 2024 Sep 27. PMID: 39348773.

A cluster randomized trial of xylitol chewing gum for prevention of preterm birth: The PPaX trial

Valentine GC, Antony KM, Sangi-Haghpeykar H, Wood AC, Chirwa R, Petro S, Dumba M, Nanthuru D, Shope C, Mlotha-Namarika J, Wilkinson J, Aagaard J, Aagaard EJ, Seferovic MD, Levison J, Kazembe P, Aagaard KM. Med. 2024 Nov 13:100539. doi: 10.1016/j.medj.2024.10.016. PMID: 39541971.

2023

Antepartum periodontitis treatment and risk of offspring screening positive for autism spectrum disorder

Bose C†, Valentine GC†, Philips K, Boggess K, Moss K, Barros S, Marchesan J, Wu D, O’Shea TM, Peralta-Carcelen M, Goldstein R, Ramamurthy R, Beck JD. J Perinatol. 2023 Apr;43(4):470-476. doi: 10.1038/s41372-023-01610-x. PMID: 36697694.
†Co-first authors

Considering Risks to Researchers and Staff in Low-Resource Settings during Public Health Crises: A Proposed Conceptual Model

Perez KM, Asim M, Weiss EM, Valentine GC, Kavi A, Somannavar MS, Iwuh I, Chiweza C, Tickell KD, Singa BO, Beima-Sofie K, Batra M, Walson JL, Umoren R, Kelley M, Saleem S. Children (Basel). 2023 Feb 26;10(3):463. doi: 10.3390/children10030463. PMID: 36980021; PMCID: PMC10047058.

Early Fluid and Nutritional Management of Extremely Preterm Newborns During the Fetal-To-Neonatal Transition

Valentine GC, Perez K, Hair AB. Clin Perinatol. 2023 Sep;50(3):545-556. doi: 10.1016/j.clp.2023.04.002. Epub 2023 May 12. PMID: 37536763.

Reducing Severe Intraventricular Hemorrhage in Preterm Infants With Improved Care Bundle Adherence

Kolnik SE, Upadhyay K, Wood TR, Juul SE, Valentine GC. Pediatrics. 2023;152(3):e2021056104. doi: 10.1542/peds.2021-056104. PMID: 37609772.

Preterm infants variability in cerebral near-infrared spectroscopy measurements in the first 72-h after birth

Kolnik SE, Marquard R, Brandon O, Puia-Dumitrescu M, Valentine GC, Law JB, Natarajan N, Dighe M, Mourad PD, Wood TR, Mietzsch U. Pediatr Res. 2023 Oct;94(4):1408-1415. doi: 10.1038/s41390-023-02618-x. Epub 2023 May 3. PMID: 37138026.

Nonsurgical periodontal treatment during pregnancy and rates of preterm birth

Valentine GC, Perez KM, Tsegaye AT, Enquobahrie DA, Couper D, Beck JD, Umoren R, Aagaard KM, McKinney CM. AJOG Global Reports. 2023. doi: 10.1016/j.xagr.2023.100180. PMID: 36876161; PMCID: PMC9975275.

2022

The Potential Role of Maternal Periodontitis on Preterm Birth and Adverse Neonatal Neurologic Outcomes

Valentine GC, Juul SE. Newborn, 2022 | doi: 10.5005/jp-journals-11002-0008.

Advancement of Enteral Feeding in Very-low-birth-weight Infants: Global Issues and Challenges

Perez K, Valentine GC, Nangia S, Burrin DG, Maheshwari A, Abayneh M, Workneh R, Jerome M, Dinerstein A, Salas A. Newborn, 2022 | doi: 10.5005/jp-journals-11002-0038.

Postnatal maximal weight loss, fluid administration, and outcomes in extremely preterm newborns

Valentine GC†, Perez KM†, Wood TR, Mayock DE, Comstock BA, Puia-Dumitrescu M, Heagerty PJ, Juul SE. J Perinatol, 2022 | doi: 10.1038/s41372-022-01369-7. PMID: 35338252.
†Co-first authors

Perinatal COVID-19 outcomes: evaluating the strength of current evidence

Sulentic RO, Seferovic MD, Aagaard KM, Valentine GC. J Matern Fetal Neonatal Med, 2022 | doi: 10.1080/14767058.2020.1849101. PMID: 33249963.

A neonatal intravenous monitor prototype

Silva J, Jeong E, Lam C, Valentine GC, Wilson DM. IEEE Sensors Letters, 2022 | doi: 10.1109/LSENS.2022.3218770.

Increasing Sodium Variability in the First 96 Hours after Birth is Associated with Adverse In-Hospital Outcomes of Preterm Newborns

Brandon O, Perez KM, Kolnik SE, Juul SE, Wood TR, Valentine GC. Curr Dev Nutr. 2022 Dec 27;7(1):100026. doi: 10.1016/j.cdnut.2022.100026. PMID: 37181132.

2021

Crossing Boundaries: Mentorship in Global Health

Brasher M, Valentine GC. Pediatrics, 2021 | doi: 10.1542/peds.2020-002154. PMID: 33419868.

Early inadequate or excessive weight loss: A potential contributor to mortality in premature newborns in resource-scarce settings?

Valentine GC, Umoren RA, Perez KM. Pediatr Neonatol, 2021 | doi: 10.1016/j.pedneo.2021.01.004. PMID: 33678594.

Percent mother’s own milk feedings for preterm neonates predicts discharge feeding outcomes

Valentine G, Ford S, Hagan J, Yang H, Chen J, Hurst N, Aagaard K, Hair A. J Perinatol, 2021 | doi: 10.1038/s41372-021-01205-4. PMID: 34526659.

2020

Community Empowerment Through Education: The Inherent Foundation of Promoting Solidarity in Global Health Research

Valentine GC, Perez K, Weiss EM. Am J Bioeth, 2020 | doi: 10.1080/15265161.2020.1745941. PMID: 32364481.

Global health training during neonatal fellowship: fellow and program director perspectives

Rent S, Valentine GC, Ehret D, Kukora S. J Perinatol, 2020 | doi: 10.1038/s41372-020-0639-8. PMID: 32152489.

The “Baby Moses” law: A case for improving medicolegal education for pediatric trainees

Valentine GC, Althouse MH, Fernandes CJ. J Med Educ Curric Dev, 2020 | doi: 10.1177/2382120520913955. PMID: 33029556.

Neonatal mortality rates and association with antenatal corticosteroids at Kamuzu Central Hospital

Valentine GC, Chiume M, Hagan J, Kazembe P, Aagaard KM, Patil M. Early Hum Dev, 2020 | doi: 10.1016/j.earlhumdev.2020.105158. PMID: 32871453.

2019

Clinical Importance of Placental Testing among Suspected Cases of Congenital Zika Syndrome

Seferovic MD†, Turley M†, Valentine GC†, Rac M, Castro ECC, Major AM, Sanchez B, Eppes C, Sanz-Cortes M, Dunn J, Kautz TF, Versalovic J, Muldrew KL, Stout T, Belfort MA, Demmler-Harrison G, Aagaard KM. Int J Mol Sci, 2019 | doi: 10.3390/ijms20030712. PMID: 30736425.
†Co-first authors

The Neonatal Microbiome and Metagenomics: What Do We Know and What Is the Future?

Valentine GC, Prince A, Aagaard KM. Neoreviews, 2019 | doi: 10.1542/neo.20-5-e258. PMID: 31126107.

The Development of the Human Microbiome: Why Moms Matter

Chu DM, Valentine GC, Seferovic MD, Aagaard KM. Gastroenterol Clin North Am, 2019 | doi: 10.1016/j.gtc.2019.04.004. PMID: 31383276.

2018

Clinical assessment and brain findings in a cohort of mothers, fetuses and infants infected with ZIKA virus

Sanz Cortes M, Rivera AM, Yepez M, Guimaraes CV, Diaz Yunes I, Zarutskie A, Davila I, Shetty A, Mahadev A, Serrano SM, Castillo N, Lee W, Valentine G, Belfort M, Parra G, Mohila C, Aagaard K, Parra Saavedra M. Am J Obstet Gynecol, 2018 | doi: 10.1016/j.ajog.2018.01.012. PMID: 29353032.

Relationships Between Perinatal Interventions, Maternal-Infant Microbiomes, and Neonatal Outcomes

Valentine GC, Chu DM, Stewart CJ, Aagaard KM. Clin Perinatol, 2018 | doi: 10.1016/j.clp.2018.01.008. PMID: 29747892.

Timing of gestational exposure to Zika virus is associated with postnatal growth restriction in a murine model

Valentine GC, Seferovic MD, Fowler SW, Major AM, Gorchakov R, Berry R, Swennes AG, Murray KO, Suter MA, Aagaard KM. Am J Obstet Gynecol, 2018 | doi: 10.1016/j.ajog.2018.06.005. PMID: 29902449.

2017

Refractory Seizures in a Term Neonate Due to Pyridoxine Dependent Epilepsy

Valentine G, Lyons-Warren AM, Seto ES, Davies J. Neurol Disord Therap, 2017 | doi: 10.15761/NDT.1000109.

A 3-Week-Old with an Isolated “Blueberry Muffin” Rash

1Darby J, Valentine G, Hillier K, Hunt R, Healy CM, Smith V, Allen-Rhoades W. Pediatrics, 2017 | doi: 10.1542/peds.2016-2598. PMID: 28759392.

2016

Zika Virus-Associated Microcephaly and Eye Lesions in the Newborn

Valentine G, Marquez L, Pammi M. J Pediatric Infect Dis Soc, 2016 | doi: 10.1093/jpids/piw037. PMID: 27405738.

Zika virus epidemic: an update

Valentine G, Marquez L, Pammi M. Expert Rev Anti Infect Ther, 2016 | doi: 10.1080/14787210.2016.1245614. PMID: 27712118.

2014

Chronic Granulomatous Disease Presenting as Hemophagocytic Lymphohistiocytosis: A Case Report

Valentine G, Thomas TA, Nguyen T, Lai YC. Pediatrics, 2014 | doi: 10.1542/peds.2014-2175. PMID: 25422023.